Cakina, SuatAydin, BuketBeyazit, Fatma2025-01-272025-01-2720200951-35901473-0766https://doi.org/10.1080/09513590.2020.1769062https://hdl.handle.net/20.500.12428/25301This study aimed to study the dynamic thiol/disulfide homeostasis in pregnant women with gestational diabetes mellitus (GDM). Forty-five pregnant women with GDM and 45 age-matched healthy pregnancies were included in this study. Thiol/disulfide homeostasis was measured using a commercial kit (Rel Assay Diagnostics). The patients with GDM had significantly higher disulfide concentrations than healthy pregnant patients (p = .001). Besides, the GDM group had significantly higher disulfide/total thiol, disuplhide/native thiol, and native thiol/total thiol ratio than healthy pregnant patients (p = .001, p = .001 and p = .001, respectively). The significantly higher concentrations of disulfide, disulfide/total thiol, disuplhide/native thiol, and native thiol/total thiol ratio in women with GDM could be considered as the increased oxidative stress.eninfo:eu-repo/semantics/closedAccessOxidative stressthioldisulfide homeostasisgestational diabetes mellitusArticle36111006100910.1080/09513590.2020.1769062Q3WOS:0005379371000012-s2.0-8508551903732436414Q2