Ozay, HavaBaran, YakupMiyamae, Hiroshi2025-01-272025-01-2720110095-89721029-0389https://doi.org/10.1080/00958972.2011.574128https://hdl.handle.net/20.500.12428/21939Kinetics of complex formation and stability constants of tetra-(2-hydroxpropyl) substituted cyclam (L-3) and cyclen (L-4) with copper(II) have been studied in aqueous solution at room temperature. These data are compared to the corresponding parent compounds (cyclam L-1 and cyclen L-2) in an attempt to define the effect of pendant arm upon kinetics and stability constants of the complexes. The kinetics were observed by stopped-flow measurements followed at multiwavelengths. These ligands were chosen to furnish information concerning effect of pendant groups and cavity size on the kinetics and stability of the complexes. Stopped-flow and spectrophotometric titration techniques were used for evaluation of the kinetics and stability constants, respectively. The apparent rate constants increase as CuL3 > CuL4 > CuL1 > CuL2. Activation parameters and stability constants of the complexes were estimated. The effect of cavity size on the rate of reaction can be observed in CuL3 > CuL4 and CuL1 > CuL2 and the effect of pendant groups in CuL3 > CuL1 and CuL4 > CuL2. Mechanism of the complex formation reaction is proposed. The enhanced stability of the copper(II) complexes formed with L-1 and L-2 macrocyclic ligands is compared to those formed with analogous pendant arm species.eninfo:eu-repo/semantics/closedAccessKineticsStabilityPendant armCavity sizeStopped-flowSpectroscopic titrationArticle6481469148010.1080/00958972.2011.574128Q3WOS:0002904056000012-s2.0-84891920176Q3