Kaymaz, BurakBuyukdogan, KadirKaymaz, NazanKomorcu, ErkamGolge, Umut HatayGoksel, FerdiAksoy, Mehmet Cemalettin2025-01-272025-01-2720161120-70001724-6067https://doi.org/10.5301/hipint.5000381https://hdl.handle.net/20.500.12428/25776Legg-Calve-Perthes disease (LCPD) is the idiopathic avascular necrosis of the femoral head in childhood. The pathologic changes seen in the femoral head are likely a result of vascular factors. Blood neutrophil to lymphocyte (N/L) ratio is a simple marker of subclinical inflammation. This study aims to to analyse the predictive ability of N/L ratio for the prognosis in LCPD patients. Methods: Patients who had been diagnosed as LCPD from 2008 to 2014 were investigated retrospectively and 40 LCPD patients (33 male and 7 female) and 25 healthy age and sex-matched children (controls) were included in the study. LCPD patients were divided into 2 groups according to expected prognosis (good prognosis expected Herring A and B patients as Group I and poor prognosis expected Herring B-C and C patients as Group II) and healthy children (control) were included in Group III. All the patients' hematological markers were analysed. Results: Mean age was 7.1 +/- 2.0 years in group I (4.9-12 years), 8.3 +/- 2.2 years (4-12.5 years) in group II and 7.8 +/- 1.3 years (6-12 years) in group III. Mean values for Groups I, II and III for neutrophil to lymphocyte (N/L) ratio were 1.13 +/- 0.65, 1.75 +/- 0.95, 1.08 +/- 0.37, respectively. The mean neutrophil to lymphocyte (N/L) ratio of Group II was higher than the other 2 groups (p = 0.003). Conclusions: N/L ratio may give us information about the natural course of LCPD and may be used as independent predictor of prognosis in patients with LCPD.eninfo:eu-repo/semantics/closedAccessNeutrophil to lymphocyte ratioPerthesPrognosisArticle26659860110.5301/hipint.5000381Q3WOS:0003885044000182-s2.0-8500036633827229163Q1