Polat-Cakir, SidikaBeksultanova, NurzhanDogan, Ozdemir2025-01-272025-01-2720181042-65071563-5325https://doi.org/10.1080/10426507.2018.1513521https://hdl.handle.net/20.500.12428/21175A series of unactivated racemic and chiral aziridine-2-phosphonates were synthesized by modified Gabriel-Cromwell reaction. Ring opening reaction of the synthesized phosphonates by gaseous HCl provided access to a wide range of biologically interesting novel beta-chloro-alpha-aminophosphonates. All reactions toward each of the above-mentioned products can be conducted regioselectively in high yields. [GRAPHICS] .eninfo:eu-repo/semantics/closedAccessAziridine-2-phosphonatesregioselective ring openingbeta-chloro-alpha-aminophosphonatesSynthesis of ?-chloro-?-aminophosphonate derivatives via the regioselective ring opening of unactivated aziridine-2-phosphonatesArticle1931285886410.1080/10426507.2018.1513521Q4WOS:0004570343000082-s2.0-85054600894Q3