Küçük, UğurKırılmaz, Bahadır2025-01-272025-01-2720232359-4802https://doi.org/10.36660/ijcs.20220208https://hdl.handle.net/20.500.12428/13262Background: Coronavirus disease (COVID-19) can cause permanent damage to vascular structures by directly or indirectly affecting the cardiopulmonary system. Lipoprotein(a) [Lp(a)] is an important identified risk factor for vascular endothelial cell dysfunction. Objective: The aim of this study was to reveal the relationship between Lp(a) levels measured at the time of COVID-19 diagnosis and the pulmonary artery (PA) to the ascending aorta (Ao) ratio (PA:Ao ratio) in survivors evaluated by transthoracic echocardiography (TTE). Methods: The study sample consisted of 100 patients who recovered from COVID-19 in the past 3 to 6 months. The relationship between the change in the PA:Ao ratio (?PA:Ao) and the Lp(a) levels measured at the time of diagnosis was evaluated. Diameter measurements at baseline and follow-up were evaluated with TTE. Results: A significant increase was found in PA, Ao, and epicardial adipose tissue (EAT) thickness in TTE (p< 0.001 for all). There was a weak correlation between D-dimer and high-sensitivity cardiac troponin measured at the time of diagnosis and ?PA:Ao and ?EAT in survivors. However, a positive and strong correlation was observed between Lp(a) levels and ?Pa:Ao (r = 0.628, p< 0.001) and ?EAT (r = 0.633, p< 0.001). Conclusion: There may be dysfunction in vascular structures due to COVID-19. For the first time in the literature, a strong correlation was shown between the Lp(a) levels measured at the time of diagnosis and ?PA:Ao and ?EAT values in patients with COVID-19. © 2023, Sociedade Brasileira de Cardiologia. All rights reserved.eninfo:eu-repo/semantics/openAccessAorta, Thoracic; COVID-19; Echocardiography; Lipoprotein(a); Pulmonary ArteryArticle3610.36660/ijcs.202202082-s2.0-85176781273Q4