Kocak, ErdemAkbal, ErdemKoklu, SeyfettinAdam, Gurhan2025-01-272025-01-2720151306-696Xhttps://doi.org/10.5505/tjtes.2015.49879https://search.trdizin.gov.tr/tr/yayin/detay/197920https://hdl.handle.net/20.500.12428/20729BACKGROUND: The aim of this study was to assess the serum L-FABP levels in patients with acute pancreatitis and compare with healthy subjects. METHODS: Thirty patients with acute pancreatitis and thirty consecutive healthy age-and sex-matched control subjects were included into the study. The serum levels of L-FABP were measured upon admission and at the remission period. RESULTS: Upon admission, serum L-FABP concentration was significantly higher in patients with acute pancreatitis compared to control subjects (41009.41 +/- 32401.31 pg/ml vs. 17057.00 +/- 5015.74 pg/ml, p=0.008). Serum L-FABP levels decreased after the remission period; however, the differences were not statistically significant. In addition, serum L-FABP levels showed significant correlation with AST and LDH levels. CONCLUSION: Increased serum L-FABP levels may be related to the mechanism of pancreatic microcirculatory disturbance in patients with acute pancreatitis, suggesting that serum L-FABP could be used for a potential biomarker of acute pancreatitis.eninfo:eu-repo/semantics/openAccessAcute pancreatitisdiagnosisserum L-FABPArticle211394310.5505/tjtes.2015.49879Q4WOS:0003515448000072-s2.0-8492303917119792025779711Q3