Ukinc, KubilayBayraktar, MiyaseGedik, Arzu2025-01-272025-01-2720091355-008X1559-0100https://doi.org/10.1007/s12020-009-9200-4https://hdl.handle.net/20.500.12428/25787Thyroid dermopathy is not a frequent feature of hyperthyroid Graves' disease, being present in less than 5% of the patients. Graves' disease has been shown to exist in euthyroid or hypothyroid forms in untreated patients. Here, we describe a case of hypothyroid Graves' disease with elephantiasis nostras verrucosa (ENV), which is an extreme form of thyroid dermopathy (TD). A 58-year-old female patient was admitted to the emergency department with somnolence, hypothermia, and bradycardia. Her mental status gradually worsened, resulting in a deep coma. She was intubated and followed in the intensive care unit, as she needed mechanical ventilatory assistance due to respiratory failure. She also had bilateral non-pitting edema, a cobblestone-like appearance, and hyperkeratotic greenish-brown-colored lesions in the pretibial and dorsal regions of the feet that were compatible with ENV. Hypothyroid Graves' disease is a very rare condition among autoimmune thyroid disorders, and ENV is an extremely rare form of TD. Here, we present a patient with hypothyroid Graves' disease and ENV.eninfo:eu-repo/semantics/closedAccessHypothyroid Graves'Autoimmune thyroid diseaseThyroid dermopathyElephantiasis nostras verrucosaReview Article3616910.1007/s12020-009-9200-4Q4WOS:0002677810000022-s2.0-7034956848819390996Q2