Bardakcı, OkanDaş, MuratŞehitoğlu, HilalÇetin, Ece ÜnalAtalay, ÜnzileKüçük, UğurKamış, Fatih2025-05-292025-05-2920222636-8579https://doi.org/10.32322/jhsm.1096501https://hdl.handle.net/20.500.12428/31029THD-2020-3255Background: S100A8/A9 and S100A12 which are the major calcium-binding proinflammatory proteins secreted by granulocytes, has been proposed to be related to distinct disease states of inflammatory origin. This study aims to explore the circulating levels of S100A8/A9 and S100A12 in acute pancreatitis (AP) and reveal their relationship with conventional inflammatory markers. Material and Method: Serum S100A8/A9 and S100A12 were determined in AP patients (male/female: 17/13) by using a specific enzyme-linked immunosorbent assay (ELISA) method at both onset and remission and in 30 healthy controls (male/female: 17/13). Results: Significantly higher S100A8/A9 and S100A12 levels were found in AP patients compared to healthy controls (peninfo:eu-repo/semantics/openAccessAcute pancreatitisS100A8/A9S100A12CRPinflammationResearch Article5384484910.32322/jhsm.1096501