Biosensor approaches on the diagnosis of neurodegenerative diseases: Sensing the past to the future

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dc.authorid0000-0003-3042-1087en_US
dc.authorscopusid6506764918en_US
dc.authorwosidAAY-1439-2021en_US
dc.contributor.authorSonuç Karaboğa, Münteha Nur
dc.contributor.authorSezgintürk, Mustafa Kemal
dc.date.accessioned2023-05-16T07:34:01Z
dc.date.available2023-05-16T07:34:01Z
dc.date.issued2022en_US
dc.departmentFakülteler, Mühendislik Fakültesi, Biyomühendislik Bölümü
dc.description.abstractEarly diagnosis of neurodegeneration-oriented diseases that develop with the aging world is essential for improving the patient's living conditions as well as the treatment of the disease. Alzheimer's and Parkinson's diseases are prominent examples of neurodegeneration characterized by dementia leading to the death of nerve cells. The clinical diagnosis of these diseases only after the symptoms appear, delays the treatment process. Detection of biomarkers, which are distinctive molecules in biological fluids, involved in neurodegeneration processes, has the potential to allow early diagnosis of neurodegenerative diseases. Studies on biosensors, whose main responsibility is to detect the target analyte with high specificity, has gained momentum in recent years with the aim of high detection of potential biomarkers of neurodegeneration process. This study aims to provide an overview of neuro-biosensors developed on the basis of biomarkers identified in biological fluids for the diagnosis of neurodegenerative diseases such as Alzheimer's disease (AD), and Parkinson's disease (PD), and to provide an overview of the urgent needs in this field, emphasizing the importance of early diagnosis in the general lines of the neurodegeneration pathway. In this review, biosensor systems developed for the detection of biomarkers of neurodegenerative diseases, especially in the last 5 years, are discussed.en_US
dc.identifier.citationKaraboğa, M. N. S., & Sezgintürk, M. K. (2022). Biosensor approaches on the diagnosis of neurodegenerative diseases: Sensing the past to the future. Journal of Pharmaceutical and Biomedical Analysis, 209 doi:10.1016/j.jpba.2021.114479en_US
dc.identifier.doi10.1016/j.jpba.2021.114479
dc.identifier.issn0731-7085
dc.identifier.issn1873-264X
dc.identifier.pmid34861607
dc.identifier.scopus2-s2.0-85120160116
dc.identifier.urihttps://doi.org/10.1016/j.jpba.2021.114479
dc.identifier.urihttps://hdl.handle.net/20.500.12428/4182
dc.identifier.volume209en_US
dc.identifier.wosWOS:000736852300004
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorSezgintürk, Mustafa Kemal
dc.language.isoen
dc.publisherElsevier B.V.en_US
dc.relation.ispartofJournal of Pharmaceutical and Biomedical Analysisen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBiosensor approacheen_US
dc.subjectBiomarkersen_US
dc.subjectNeurodegenerative Diseasesen_US
dc.subjectBiosensing Techniquesen_US
dc.subjectAlzheimer Diseaseen_US
dc.subjectParkinson Diseaseen_US
dc.titleBiosensor approaches on the diagnosis of neurodegenerative diseases: Sensing the past to the future
dc.typeReview Article

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