The Quantitative Evaluation of the Density of the Segmental Branches of the MCA in Acute Ischemic Stroke Patients

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dc.contributor.authorDemirtas, Erdal
dc.contributor.authorOztoprak, Ibrahim
dc.date.accessioned2025-01-27T20:26:54Z
dc.date.available2025-01-27T20:26:54Z
dc.date.issued2020
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractAim: The aim of this study was to assess the density of the segmental branches of the middle cerebral artery (MCA) quantitatively as a predictor of acute ischemic stroke in patients without definitive infarct findings at cerebral parenchyma by non-contrast computed tomography (CT). Clinical rationale for the study: The clinical rationale for the study is to evaluate if the measurement of Sylvian fissure dot sign (SDS) would help early management of patients with stroke at the emergency department. Methods: Computed tomography scans of 101 patients admitted to the emergency department with stroke symptoms and/or signs were included in the study, retrospectively. In the patient group, the quantitative density of the segmental branches of the MCA in the Sylvian fissure was measured on the affected side and the contralateral side. Results: Quantitative density of SDS was significantly higher on the ischemic side of the brain. Receiver operating characteristic (ROC) analysis showed a cut-off value of 38.5 Hounsfield units (HU) as a predictor for acute ischemic stroke, with a sensitivity and specificity of 79% and 92%, respectively. Conclusion: Quantitative density of SDS on the affected side in patients without definitive cerebral infarct findings of parenchyma can be used in the emergency room as an objective predictor sign for the diagnosis of acute ischemic stroke. Considering this finding in the differential diagnosis of acute stroke patients in the emergency room has the potential to improve their clinical management, particularly for the patients without early parenchymal and vascular signs of stroke.
dc.identifier.doi10.5041/RMMJ.10407
dc.identifier.issn2076-9172
dc.identifier.issue4
dc.identifier.pmid32516109
dc.identifier.scopus2-s2.0-85095988701
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.5041/RMMJ.10407
dc.identifier.urihttps://hdl.handle.net/20.500.12428/22488
dc.identifier.volume11
dc.identifier.wosWOS:000581132800011
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherRambam Health Care Campus
dc.relation.ispartofRambam Maimonides Medical Journal
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectAcute ischemic stroke
dc.subjectcomputed tomography
dc.subjectdensity
dc.subjectMCA Sylvian branches
dc.titleThe Quantitative Evaluation of the Density of the Segmental Branches of the MCA in Acute Ischemic Stroke Patients
dc.typeArticle

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