Three species of Verbascum L. from Northwest Anatolia of Turkey as a source of biological activities

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dc.contributor.authorDoğru, Nurcihan Hacıoğlu
dc.contributor.authorDemir, Neslihan
dc.contributor.authorYılmaz, Özer
dc.date.accessioned2025-01-27T19:36:48Z
dc.date.available2025-01-27T19:36:48Z
dc.date.issued2021
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractPhytochemical constituents, and some biological activities i.e. antimutagenicity, DNA damage protecting, antioxidant, antibacterial and antibiofilm of ethanolic extracts of three Verbascum plants (Verbascum mucronatum Lam., V. bombyciferum Boiss., V. vacillans Murb.) were studied. This paper is the first comprehensive research on V. mucronatum, V. bombyciferum, V. vacillans biological activities. V. vacillans ethanol extract has been determined to be lowest plant for phytochemical contents. In 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging activity three plants extracts showed concentration-dependent antioxidant capacity higher than butylated hydroxytoluene (BHT). V. mucronatum and V. bombyciferum extracts exhibited strong antimutagenic effect on Salmonella typhimurium TA98 and TA100 strains. Verbascum extracts showed DNA damage protection potential in tested concentrations. However, the lowest concentration (0.5 ?M) of the V. bombyciferum species Form III were observed and almost completely disintegrate DNA in this concentration. Three Verbascum plants were showed strong antibacterial activities with inhibition zones at 9.0 – 19.0 mm and significant reduction in biofilm formation. It was observed that these plants are potential source of various biological activities.
dc.identifier.doi10.51435/turkjac.886692
dc.identifier.endpage26
dc.identifier.issn2687-6698
dc.identifier.issue1
dc.identifier.startpage19
dc.identifier.trdizinid1111231
dc.identifier.urihttps://doi.org/10.51435/turkjac.886692
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1111231
dc.identifier.urihttps://hdl.handle.net/20.500.12428/16992
dc.identifier.volume3
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofTurkish Journal of Analytical Chemistry (Online)
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_TRD_20250125
dc.subjectBiyoloji
dc.subjectKimya
dc.subjectTıbbi
dc.subjectÇevre Bilimleri
dc.subjectEkoloji
dc.titleThree species of Verbascum L. from Northwest Anatolia of Turkey as a source of biological activities
dc.typeArticle

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