The Role of Pneumococcal Pneumonia among CommunityAcquired Pneumonia in Adult Turkish Population: TurkCAP Study
Citation
Şenol, E., Çilli, A., Günen, H., Şener, A., Dumlu, R., Ödemiş, A., Topçu, A., Yıldız, Y., Güner, R., Özhasenekler, A., Mutlu, B., Köktürk, N., Sevimli, N., Baykam, N., Yapar, D., Ekin, S., Polatlı, M., Gök, Ş., Kılınç, O., Sayıner, A., Karaşahin, Ö., Çuhadaroğlu, Ç., Kocagöz, A., Togan, T., Arpağ, H., Katı, H., Köksal, İ., Aksoy, F., Hasanoğlu, C. (2021). The Role of Pneumococcal Pneumonia among Community Acquired Pneumonia in Adult Turkish Population:TurkCAP Study. Turkish Thoracic Journal, 22(4), 339 - 345. 10.5152/TurkThoracJ.2021.20223 Abstract
OBJECTIVE: To evaluate the rate of pneumococcal pneumonia (PP) among patients with community-acquired pneumonia (CAP) in Turkey and to investigate and compare features of PP and non-PP CAP patients.
MATERIAL AND METHODS: This multicenter, non-interventional, prospective, observational study included adult CAP patients (age = 18 years). Diagnosis of PP was based on the presence of at least 1 positive laboratory test result for Streptococcus pneumoniae (blood culture or sputum culture or urinary antigen test [UAT]) in patients with radiographic findings of pneumonia.
RESULTS: Four hundred sixty-five patients were diagnosed with CAP, of whom 59 (12.7%) had PP. The most common comorbidity was chronic obstructive pulmonary disease (30.1%). The mean age, smoking history, presence of chronic neurological disease, and CURB-65 score were significantly higher in PP patients, when compared to non-PP patients. In PP patients, 84.8% were diagnosed based ony on the UAT. The overall rate of PP patients among CAP was calculated as 22.8% considering the UAT sensitivity ratio of 63% (95% confidence interval: 45-81). The rate of intensive care treatment was higher in PP patients (P =.007). While no PP patients were vaccinated for pneumococcus, 3.8% of the non-PP patients were vaccinated (P =.235). Antibiotic use in the preceding 48 hours was higher in the non-PP group than in the PP group (31.8% vs. 11.1%, P =.002). The CURB-65 score and the rate of patients requiring inpatient treatment according to this score were higher in the PP group.
CONCLUSION: The facts that PP patients were older and required intensive care treatment more frequently as compared to non-PP patients underline the burden of PP.
