Now showing items 1-5 of 5
Possible protective activity of n‑acetyl cysteine against cisplatin‑induced hepatotoxicity in rats
CP is one of the most widely used antineoplastic agents. However, its clinical application is very limited due to its severe toxic efects. The present study aimed to reveal the efects of NAC, which exhibits broad biological ...
Alterations in aquaporin gene expression level on cyclophosphamide-induced cardiac injury and possible protective role of Ganoderma lucidum
This research study was conducted to investigate the cardioprotective activity of alcoholic extract of Ganoderma lucidum (GL) against cyclophosphamide (CYP)-induced cardiotoxicity in rats model. Therewithal, the regulation ...
Recuperative effect of estrogen on rotenone-induced experimental model of Parkinson’s disease in rats
Parkinson’s disease (PD) is described as the loss of dopaminergic neurons located in the substantia nigra (SN) region of the brain and a progressive motor failure. Increased frequency of PD in women, especially after ...
The role of AQP3 and AQP4 channels in cisplatin‑induced cardiovascular edema and the protective efect of melatonin
Background The present study evaluates the development of edema, the change in the AQP3, AQP4, p53 and Bax gene expressions, and the protective efects of melatonin in rat hearts administered with cisplatin. Methods and ...
The effect of medical ozone on oxidative stress and neuroinflammation in the early stage after experimental status epilepticus
Preservation of the brain is important to reducing recurrent seizures and other neurological sequelae after status epilepticus (SE). Medical ozone (MedO3) shows antioxidant, anti-inflammatory and anti-apoptotic properties ...