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Possible protective activity of n‑acetyl cysteine against cisplatin‑induced hepatotoxicity in rats
CP is one of the most widely used antineoplastic agents. However, its clinical application is very limited due to its severe toxic efects. The present study aimed to reveal the efects of NAC, which exhibits broad biological ...
The role of AQP3 and AQP4 channels in cisplatin‑induced cardiovascular edema and the protective efect of melatonin
Background The present study evaluates the development of edema, the change in the AQP3, AQP4, p53 and Bax gene expressions, and the protective efects of melatonin in rat hearts administered with cisplatin. Methods and ...