Browsing by Author "Sezgintürk, Mustafa Kemal"
Now showing items 1-20 of 25
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Akut böbrek hasarının potansiyel biyomarkerlarından KIM-1 tayini için elektrokimyasal immünosensör sisteminin geliştirilmesi
Şentürk, Şeyma (Çanakkale Onsekiz Mart Üniversitesi, 2023)Böbrek Hasarı Molekülü-1 (KIM-1), bir tip I transmembran glikoproteinidir ve akut böbrek hasarı durumunda idrarda seviyesinin değişkenlik gösterdiği için böbrek hasarını saptamak adına potansiyel bir biyomarkerdır. Tez ... -
Anti-sitrullinlenmiş protein antikorları için elektrokimyasal biyosensör geliştirilmesi ve uygulaması
Uzman, Ecem (Çanakkale Onsekiz Mart Üniversitesi, Lisansüstü Eğitim Enstitüsü, 2023)Romatoid Artrit (RA) eklem hasarına sebep olan kronik bir otoimmün inflamatuar hastalıktır. Son zamanlarda Anti-sitrullinlenmiş protein antikorları (ACPA), RA teşhisi için yüksek özgüllükleri sebebiyle biyobelirteç olarak ... -
Biosensing strategies for diagnosis of prostate specific antigen
Özyurt, Canan; Uludağ, İnci; Sezgintürk, Mustafa Kemal (Elsevier B.V., 2022)Almost from the time of its discovery, the prostate specific antigen (PSA) has been one of the most accurate and most extensively studied indicators of prostate cancer (PC). Because of advancements in biosensing systems ... -
Biosensor approaches on the diagnosis of neurodegenerative diseases: Sensing the past to the future
Sonuç Karaboğa, Münteha Nur; Sezgintürk, Mustafa Kemal (Elsevier B.V., 2022)Early diagnosis of neurodegeneration-oriented diseases that develop with the aging world is essential for improving the patient's living conditions as well as the treatment of the disease. Alzheimer's and Parkinson's ... -
Biosensors for saliva biomarkers
Aydın, Elif Burcu; Aydın, Muhammet; Sezgintürk, Mustafa Kemal (Academic Press Inc., 2023)The analysis of salivary biomarkers has gained interest and is advantageous for simple, safe, and non-invasive testing in diagnosis as well as treatment. This chapter explores the importance of saliva biomarkers and ... -
Detection of Kallikrein-Related Peptidase 4 with a Label-free Electrochemical Impedance Biosensor Based on a Zinc(II) Phthalocyanine Tetracarboxylic Acid-Functionalized Disposable Indium Tin Oxide Electrode
Aydın, Elif Burcu; Aydın, Muhammet; Yüzer, Abdülcelil; İnce, Mine; Ocakoğlu, Kasım; Sezgintürk, Mustafa Kemal (Amer Chemical Soc, 2021)A new impedimetric biosensing system based on kallikrein-related peptidase 4 (KLK 4) antigen-specific antibodies and a zinc(II) phthalocyanine tetracarboxylic acid (Zn-PcTCa) matrix material was developed for the first ... -
Electrochemical immunosensors based on quantum dots
Karaboğa, Münteha Nur Sonuç; Sezgintürk, Mustafa Kemal (Elsevier, 2021)The use of quantum dot-based electrochemical immunosensors in a wide perspective from disease markers to agriculture has gained importance in recent years. Due to this importance, many signal amplification strategies have ... -
Fabrication of electrochemical immunosensor based on acid-substituted poly(pyrrole) polymer modified disposable ITO electrode for sensitive detection of CCR4 cancer biomarker in human serum
Aydın, Elif Burcu; Aydın, Muhammet; Sezgintürk, Mustafa Kemal (Elsevier, 2021)This study described the first impedimetric immunosensor reported for the determination of CCR4, a new prostate cancer biomarker. This impedimetric immunosensor was constructed through the modification of disposable indium ... -
A high sensitive and cost-effective disposable biosensor for adiponectin determination in real human serum samples
İnce, Bahar; Sezgintürk, Mustafa Kemal (Elsevier, 2021)One of the adipose tissue cytokines, adiponectin is a newly defined adipocytokin, which is involved in insulin, glucose and adipocyte metabolisms. It has been determined that the amount of adiponectin in the circulatory system ... -
Highly selective and sensitive sandwich immunosensor platform modified with MUA-capped GNPs for detection of spike Receptor Binding Domain protein: A precious marker of COVID 19 infection
Aydın, Elif Burcu; Aydın, Muhammet; Sezgintürk, Mustafa Kemal (Elsevier, 2021)A label-free electrochemical biosensing system as a suitable analysis technique for COVID 19 specific spike receptor-binding domain protein (RBD) was developed with an aim to facilitate the diagnosis of coronavirus. A novel ... -
Highly Sensitive and Single-Use Biosensing System Based on a GP Electrode for Analysis of Adiponectin, an Obesity Biomarker
Özcan, Burcu; Sezgintürk, Mustafa Kemal (Amer Chemical Soc, 2021)This study presents a disposable, novel, and sensitive biosensing system to determine adiponectin, an obesity biomarker, in real human serum. The graphite paper (GP) working electrode is a new material for impedimetric ... -
Immunosensors Based on the Technology of Molecular Imprinted Polymers
Aydın, Elif Burcu; Aydın, Muhammed; Sezgintürk, Mustafa Kemal (Elsevier, 2021)Molecularly imprinted polymer (MIP)-based biosensors have successfully been utilized for sensitive and selective biosensing of different analytes because of imprinted molecular cavities present on the transducer surface. ... -
An innovative method for the detection of alpha synuclein, a potential biomarker of Parkinson's disease: quartz tuning fork-based mass sensitive immunosensor design
Sonuç Karaboğa, Münteha Nur; Ünal, Mehmet Altay; Arı, Fikret; Sezgintürk, Mustafa Kemal; Özkan, Sibel Ayşıl (Royal Society of Chemistry, 2024)An innovative biosensing fabrication strategy has been demonstrated for the first time using a quartz tuning fork (QTF) to develop a practical immunosensor for sensitive, selective and practical analysis of alpha synuclein ... -
Lab-on-a-chip systems for cancer biomarker diagnosis
Özyurt, Canan; Uludağ, İnci; İnce, Bahar; Sezgintürk, Mustafa Kemal (Elsevier B.V., 2023)Lab-on-a-chip (LOC) or micro total analysis system is one of the microfluidic technologies defined as the adaptation, miniaturization, integration, and automation of analytical laboratory procedures into a single instrument ... -
A label-free dual immunosensor for the simultaneous electrochemical determination of CA125 and HE4 biomarkers for the early diagnosis of ovarian cancer
Bilgi Kamaç, Melike; Altun, Muhammed; Yılmaz, Merve; Sezgintürk, Mustafa Kemal (Springer Science and Business Media Deutschland GmbH, 2023)The blood levels of cancer antigen 125 (CA125) and human epididymal secretory protein 4 (HE4) are measured in the diagnosis and progression monitoring of ovarian cancer (OC), and the Risk of Ovarian Malignancy Algorithm ... -
A Label-free Electrochemical Immunosensor for Highly Sensitive Detection of TNF alpha, Based on Star Polymer-modified disposable ITO Electrode
Aydın, Elif Burcu; Aydın, Muhammet; Sezgintürk, Mustafa Kemal (Bentham Science Publishers, 2021)Background: Biomarkers are very important disease-related biomolecules which should be analyzed sensitive and selective in related physiological fluids or tissues. Tumor necrosis factor-α is a type of cytokine which plays ... -
A new immunosensing platform based on conjugated Poly(ThidEp-co-EDOT) copolymer for resistin detection, a new obesity biomarker
Aydın, Elif Burcu; Aydın, Muhammet; Sezgintürk, Mustafa Kemal (Springer, 2024)The design of a novel electrochemical impedimetric biosensor for label-free analysis of resistin, a biomarker for obesity, is reported. For the fabrication of the immunosensor, a novel approach composed of electrochemical ... -
A novel and disposable GP- based impedimetric biosensor using electropolymerization process with PGA for highly sensitive determination of leptin: Early diagnosis of childhood obesity
Özcan, Burcu; Sezgintürk, Mustafa Kemal (Elsevier, 2021)This study presents a novel, single-use electrochemical biosensor for the leptin biomarker, which may have potential use for early diagnosis of childhood obesity. The graphite paper working electrode was used for the first ... -
A novel electrochemical immunosensor based on acetylene black/ epoxy-substituted-polypyrrole polymer composite for the highly sensitive and selective detection of interleukin 6
Aydın, Elif Burcu; Aydın, Muhammet; Sezgintürk, Mustafa Kemal (Elsevier, 2021)An ultrasensitive immunosensor based on acetylene black (AB)/epoxy-substituted-poly(pyrrole) polymer (EpxS-PPyr) composite coated disposable indium tin oxide (ITO) electrode was fabricated for interleukin 6 (IL 6) detection. ... -
A novel electrochemical impedance immunosensor for the quantification of CYFRA 21-1 in human serum
Aydın, Elif Burcu; Aydın, Muhammet; Sezgintürk, Mustafa Kemal (Springer, 2023)A sensitive, simple, and reliable immunosensor was constructed to detect the lowest alteration of a fragment of cytokeratin subunit 19 (CYFRA 21-1), a protein lung carcinoma biomarker. The proposed immunosensor was ...
